PPFIA1
Sign in to saveAlso known as LIP.1, LIP1, LIPRIN, PTPRF interacting protein alpha 1
Liprin-alpha-1 is a protein that in humans is encoded by the PPFIA1 gene.
Gene data
PPFIA1- Name
- PPFI scaffold protein A1
- Type
- protein-coding
- Aliases
- LIP.1, LIP1, LIPRIN
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
PPFI scaffold protein A1
- Symbol
- PPFIA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:70,270,655-70,385,312
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 20802
- exact match
- identifiers.org/ncbigene/8500
- genomic end
- 70385312
- genomic start
- 70270690
- cytogenetic location
- 11q13.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Liprin-alpha-1 is a protein that in humans is encoded by the PPFIA1 gene.
== Function ==