PPIA
Sign in to saveAlso known as CYPA, CYPH, HEL-S-69p, Peptidylprolyl isomerase A
protein-coding gene in the species Homo sapiens
Gene data
PPIA- Name
- peptidylprolyl isomerase A
- Type
- protein-coding
- Position
- 44,796,620–44,824,564 (+)
- Aliases
- CYPA, CYPH, HEL-S-69p
- Ensembl
- ENSG00000196262
- RefSeq RNA
- NM_001300981.2, NM_021130.5, NM_203430.1, NM_203431.1, XM_047420536.1
- RefSeq protein
- NP_001287910.1, NP_066953.1, XP_047276492.1, XP_047276493.1, XP_054214491.1
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
peptidylprolyl isomerase A
- Symbol
- PPIA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:44,796,620-44,824,564
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI