PPIB
Sign in to saveAlso known as CYP-S1, CYPB, HEL-S-39, OI9, SCYLP, peptidylprolyl isomerase B, B
gene umano
Gene data
PPIB- Name
- peptidylprolyl isomerase B
- Type
- protein-coding
- Position
- 64,155,740–64,163,159 (−)
- Aliases
- CYP-S1, CYPB, HEL-S-39, OI9, SCYLP
- Ensembl
- ENSG00000166794
- RefSeq RNA
- NM_000942.5
- RefSeq protein
- NP_000933.1
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
peptidylprolyl isomerase B
- Symbol
- PPIB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:64,155,740-64,163,159
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PPIB PDB 1cyn.png
Show 9 more facts
- HomoloGene ID
- 726
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5479
- genomic end
- 64163134
- genomic start
- 64155740
- chromosome
- human chromosome 15
- cytogenetic location
- 15q22.31
- expressed in
- pericardium
- Commons category
- Peptidyl-prolyl cis-trans isomerase B
Sources (3)
via Wikidata · CC0