pyridoxal

Also known as 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde, Piridoxal, Pyridoxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl-pyridine-4-carbaldehyde, 3-hydroxy-2-methyl-5-methylol-isonicotinaldehyde

Pyridoxal (PL) is one form of vitamin B6.

Chemical data

Formula: C8H9NO3
Molecular weight: 167.16 g/mol
IUPAC name: 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde
SMILES: CC1=NC=C(C(=C1O)C=O)CO
InChIKey: RADKZDMFGJYCBB-UHFFFAOYSA-N
XLogP: 0
Polar surface area: 70.4 Å²
H-bond donors: 2
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule

via ChEMBL · EBI

Research

12,787 papers

Pyridoxal 5'-Phosphate Biosynthesis by Pyridox-(am)-ine 5'-Phosphate Oxidase: Species-Specific Features.International journal of molecular sciences · 2024
Pyridoxal isonicotinoyl hydrazone and its analogues.Advances in experimental medicine and biology · 2002
Pyridoxal isonicotinoyl hydrazone. Effective iron chelation after oral administration.Annals of the New York Academy of Sciences · 1990
Pyridoxal Reductase, PdxI, Is Critical for Salvage of Pyridoxal in Escherichia coli.Journal of bacteriology · 2020
Pyridoxal isonicotinoyl hydrazone (PIH): a promising new iron chelator.Birth defects original article series · 1988

via PubMed

Wikidata facts

Subclass of: vitamin B6
Mass: 167.058
Has use: medication

Show 5 more facts

found in taxon: soybean
chemical formula: C₈H₉NO₃
canonical SMILES: CC1=NC=C(C(=C1O)C=O)CO
subject has role: primary metabolite
Commons category: Pyridoxal

Sources (6)

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Encyclopedic overview

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Contents

See also
References

Pyridoxal (PL) is one form of vitamin B6.

Some medically relevant bacteria, such as those in the genera Granulicatella and Abiotrophia, require pyridoxal for growth. This nutritional requirement can lead to the culture phenomenon of satellite growth. In in vitro culture, these pyridoxal-dependent bacteria may only grow in areas surrounding colonies of bacteria from other genera ("satellitism") that are capable of producing pyridoxal.

Excerpted from Wikipedia’s “pyridoxal” article, available under the CC BY-SA 4.0 licence.

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