File:Pyridoxin.svg · Wikimedia Commons · See Wikimedia Commons
pyridoxine
Sign in to saveAlso known as 2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine, 3-Hydroxy-4,5-dimethylol-alpha-picoline, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, Pyridoxol, Vitamin B6, 2-methyl-4,5-dimethylol-pyridin-3-ol
Pyridoxine (PN) is a form of vitamin B6 found commonly in food and used as a dietary supplement. As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning. It is used by mouth or by injection.
OverviewAI-generated
Pyridoxine is a chemical compound with the formula C₈H₁₁NO₃. Its IUPAC name is 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol. The substance has a mass of 169.074 and a weight of 169.18. It possesses a charge of 0, an xlogp of -0.8, and a topological polar surface area of 73.6.
The molecule features three hydrogen bond donors and four hydrogen bond acceptors. Its canonical SMILES notation is CC1=NC=C(C(=C1O)CO)CO. Pyridoxine is referenced by 227 other encyclopedia articles. A search for pyridoxine in PubMed yields a count of 11243 entries.
Synthesized by Vinony from 17 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.routes_of_administration
- By mouth, intravenous (IV), intramuscular (IM), subcutaneous
- Drug.ATC_prefix
- A11
- Drug.ATC_suffix
- HA02
- Drug.legal_UK
- P
- Drug.legal_US
- OTC
- Drug.legal_US_comment
- / Rx-only
- Drug.elimination_half life
- several weeks (see #Metabolism for details)
- Drug.CAS_number
- 65-23-6
- Drug.PubChem
- 1054
- Drug.DrugBank
- DB00165
- Drug.ChemSpiderID
- 1025
- Drug.UNII
- KV2JZ1BI6Z
- Drug.KEGG
- D08454
- Drug.ChEBI
- 16709
- Drug.ChEMBL
- 1364
- Drug.synonyms
- vitamin B6, pyridoxol pyridoxine hydrochloride
- Drug.C
- 8
- Drug.H
- 11
via Wikipedia infobox
Chemical data
- Formula
- C8H11NO3
- Molecular weight
- 169.18 g/mol
- IUPAC name
- 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
- SMILES
- CC1=NC=C(C(=C1O)CO)CO
- InChIKey
- LXNHXLLTXMVWPM-UHFFFAOYSA-N
- XLogP
- -0.8
- Polar surface area
- 73.6 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
11,243 papersvia PubMed
~3 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Side effects
- Mechanism
- Metabolism
- History
- References
- External links
Pyridoxine (PN) is a form of vitamin B6 found commonly in food and used as a dietary supplement. As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning. It is used by mouth or by injection.
It is usually well tolerated. Occasionally side effects include headache, numbness, and sleepiness. Normal doses are safe during pregnancy and breastfeeding. Pyridoxine is in the vitamin B family of vitamins. It is required by the body to metabolise amino acids, carbohydrates, and lipids. Sources in the diet include meat, fish, fruit, vegetables, and grain.
Excerpted from Wikipedia’s “pyridoxine” article, available under the CC BY-SA 4.0 licence.