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pyrrole

File:Pyrrole-2D-full.svg · Wikimedia Commons · See Wikimedia Commons

EntityQ242627· pop 48· linked from 219 articles

Also known as monopyrrole, divinyleneimine, imidole, divinylenimine, 1-aza-2,4-cyclopentadiene, 1H-pyrrole, pyrrhol, azole

Pyrrole is a heterocyclic, aromatic, organic compound, a five-membered ring with the formula . It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, . Porphobilinogen, a trisubstituted pyrrole, is the biosynthetic precursor to many natural products such as heme.

Chemical data

Formula
C4H5N
Molecular weight
67.09 g/mol
IUPAC name
1H-pyrrole
SMILES
C1=CNC=C1
InChIKey
KAESVJOAVNADME-UHFFFAOYSA-N
XLogP
0.7
Polar surface area
15.8 Ų
H-bond donors
1
H-bond acceptors
0
Formal charge
0

via PubChem

Wikidata facts

Mass
67.042
Image
Pyrrole Post Distillation.jpg
Show 15 more facts
chemical formula
C₄H₅N
Commons category
Pyrrole
canonical SMILES
C1=CNC=C1
density
0.9698
melting point
-23.39
boiling point
129.74
refractive index
1.5085
pKa
-3.8
solubility
47
electric dipole moment
1.767
vapor pressure
1.10
flash point
39
surface tension
34.31
dynamic viscosity
0.612
ionization energy
8.21
Sources (3)

via Wikidata · CC0

~14 min read

Article

21 sections
Contents
  • Properties, structure, bonding
  • History
  • Occurrence in nature
  • Synthesis
  • Hantzsch pyrrole synthesis
  • Knorr pyrrole synthesis
  • Paal–Knorr pyrrole synthesis
  • Other methods
  • Biosynthesis
  • Reactions and reactivity
  • Reaction of pyrrole with electrophiles
  • Acylation
  • Reaction of deprotonated pyrrole
  • Reductions
  • Cyclization reactions
  • Commercial uses
  • Analogs and derivatives
  • See also
  • References
  • Further reading
  • External links

Pyrrole is a heterocyclic, aromatic, organic compound, a five-membered ring with the formula . It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, . Porphobilinogen, a trisubstituted pyrrole, is the biosynthetic precursor to many natural products such as heme.

Pyrroles are components of more complex macrocycles, including the porphyrinogens and products derived therefrom, including porphyrins of heme, the chlorins, bacteriochlorins, and chlorophylls.

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