RARRES2
Sign in to saveAlso known as HP10433, TIG2, Chemerin, retinoic acid receptor responder 2
Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene.
Gene data
RARRES2- Name
- retinoic acid receptor responder 2
- Type
- protein-coding
- Position
- 150,338,314–150,342,144 (−)
- Aliases
- HP10433, TIG2
- Ensembl
- ENSG00000106538
- RefSeq RNA
- NM_002889.4, XR_007060121.1, XR_008487717.1
- RefSeq protein
- NP_002880.1
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi. [provided by RefSeq, Nov 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
retinoic acid receptor responder 2
- Symbol
- RARRES2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:150,338,314-150,342,144
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~4 min read
Encyclopedic overview
5 sectionsContents
- Function
- Role as an adipokine
- Role in obesity and diabetes
- References
- Further reading
Chemerin, also known as retinoic acid receptor responder protein 2 (RARRES2), tazarotene-induced gene 2 protein (TIG2), or RAR-responsive protein TIG2 is a protein that in humans is encoded by the RARRES2 gene.
== Function ==
Excerpted from Wikipedia’s “RARRES2” article, available under the CC BY-SA 4.0 licence.