Also known as DFNB24, radixin
Radixin is a protein that in humans is encoded by the RDX gene.
Gene data
RDX- Name
- radixin
- Type
- protein-coding
- Position
- 109,864,295–110,297,617 (−)
- Aliases
- DFNB24
- Ensembl
- ENSG00000137710
- RefSeq RNA
- NM_001260492.2, NM_001260493.2, NM_001260494.2, NM_001260495.2, NM_001260496.2
- RefSeq protein
- NP_001247421.1, NP_001247422.1, NP_001247423.1, NP_001247424.1, NP_001247425.1
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
radixin
- Symbol
- RDX
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:109,864,295-110,297,617
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RDX PDB 1gc6.png
Show 10 more facts
- HomoloGene ID
- 37707
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5962
- cytogenetic location
- 11q22.3
- genomic end
- 110296712
- genomic start
- 109864295
- chromosome
- human chromosome 11
- genetic association
- nonsyndromic deafness
- expressed in
- Achilles tendon
- Commons category
- Radixin
Sources (8)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- See also
- References
- Further reading
Radixin is a protein that in humans is encoded by the RDX gene.
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
Excerpted from Wikipedia’s “RDX” article, available under the CC BY-SA 4.0 licence.