MYLIP
Sign in to saveAlso known as IDOL, MIR, myosin regulatory light chain interacting protein
Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene.
Gene data
MYLIP- Name
- myosin regulatory light chain interacting protein
- Type
- protein-coding
- Position
- 16,129,063–16,151,367 (+)
- Aliases
- IDOL, MIR
- Ensembl
- ENSG00000007944
- RefSeq RNA
- NM_001436627.1, NM_013262.4, XM_005249033.4, XM_017010789.2, XM_047418683.1
- RefSeq protein
- NP_001423556.1, NP_037394.2, XP_005249090.1, XP_016866278.1, XP_047274639.1
The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
myosin regulatory light chain interacting protein
- Symbol
- MYLIP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:16,129,063-16,151,367
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8309
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29116
- genomic end
- 16148479
- genomic start
- 16129086
- expressed in
- cardia
- chromosome
- human chromosome 6
- cytogenetic location
- 6p22.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene.
MYLIP is also known as IDOL "Inducible Degrader of the LDL receptor" based on its involvement in cholesterol regulation or MIR "Modulator Of Immune Recognition". The expression of IDOL is induced by the sterol-activated liver X receptor.
Excerpted from Wikipedia’s “MYLIP” article, available under the CC BY-SA 4.0 licence.