RFC3
Sign in to saveAlso known as RFC38, replication factor C subunit 3
Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene.
Gene data
RFC3- Name
- replication factor C subunit 3
- Type
- protein-coding
- Position
- 33,818,049–34,031,334 (+)
- Aliases
- RFC38
- Ensembl
- ENSG00000133119
- RefSeq RNA
- NM_002915.4, NM_181558.3, XM_011535172.4, XM_011535173.4, XM_011535175.3
- RefSeq protein
- NP_002906.1, NP_853536.2, XP_011533474.1, XP_011533475.1, XP_011533477.1
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
replication factor C subunit 3
- Symbol
- RFC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:33,818,049-34,031,334
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2188
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5983
- genomic end
- 34540695
- genomic start
- 33818069
- chromosome
- human chromosome 13
- cytogenetic location
- 13q13.2
- expressed in
- appendix
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Replication factor C subunit 3 is a protein that in humans is encoded by the RFC3 gene.
== Function ==
Excerpted from Wikipedia’s “RFC3” article, available under the CC BY-SA 4.0 licence.