RGS10

Name

regulator of G protein signaling 10

Type

protein-coding

Position

119,499,603–119,543,620 (−)

Ensembl

ENSG00000148908

RefSeq RNA

NM_001005339.2, NM_002925.4

RefSeq protein

NP_001005339.1, NP_002916.1

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

regulator of G protein signaling 10

Symbol

RGS10

Biotype

Protein coding

Organism

Homo sapiens

Location

10:119,499,603-119,543,620

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein RGS10 PDB 2dlr.png

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