TSC complex subunit 2
Sign in to saveAlso known as tuberous sclerosis 2 protein, tuberin, TSC2, protein phosphatase 1, regulatory subunit 160
Tuberous sclerosis complex 2 (TSC2), also known as tuberin, is a protein that in humans is encoded by the TSC2 gene.
Research
94 papers- How autophagy controls the intestinal epithelial barrier.Autophagy · 2022
- Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway.Autophagy · 2025
- Emerging dimensions of autophagy in melanoma.Autophagy · 2024
- ATM loss disrupts the autophagy-lysosomal pathway.Autophagy · 2021
- Full-coverage regulations of autophagy by ROS: from induction to maturation.Autophagy · 2022
via PubMed
Clinical Trials
4 registered- PHASE3COMPLETEDEfficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)Novartis Pharmaceuticals · NCT00790400
- PHASE3TERMINATEDAssessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled SeizuresJazz Pharmaceuticals · NCT04485104
- ENROLLING_BY_INVITATIONEarly Check: Expanded Screening in NewbornsRTI International · NCT03655223
- PHASE2UNKNOWNPhase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)Aadi Bioscience, Inc. · NCT05103358
~2 min read
Article
8 sectionsContents
- Function
- Cell pathology
- Signaling pathways
- Interactions
- See also
- References
- Further reading
- External links
Tuberous sclerosis complex 2 (TSC2), also known as tuberin, is a protein that in humans is encoded by the TSC2 gene.
== Function ==
Connections
Q180686
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Ensembl genome database project
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heat shock protein Hsp90 family
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GSK3B
Gene
protein
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Wikidata
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gene
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chromosome
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digital object identifier
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lysosome
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glycogen
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bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
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autophagy
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Online Mendelian Inheritance in Man
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ubiquitin
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