Rhodanese
Rhodanese is a mitochondrial enzyme that detoxifies cyanide (CN−) by converting it to thiocyanate (SCN−, also known as "rhodanate"). In enzymatology, the common name is listed as thiosulfate sulfurtransferase (). The diagram on the right shows the crystallographically-determined structure of rhodanese.
Key facts
- Protein family.Symbol
- Rhodanese
- Protein family.Name
- Rhodanese-like domain
- Protein family.image
- Rhodanase.png
- Protein family.Pfam
- PF00581
- Protein family.InterPro
- IPR001763
- Protein family.Prosite
- PDOC00322
- Protein family.SCOP
- 2ora
- Protein family.OPM family
- 413
- Protein family.OPM protein
- 2mpn
- Protein family.CDD
- cd00158
- Protein family.Membranome superfamily
- 571
- Enzyme.Name
- thiosulfate sulfurtransferase
Article
6 sectionsContents
- Structure and mechanism
- Clinical relevance
- Human proteins
- Nomenclature
- References
- External links
Rhodanese is a mitochondrial enzyme that detoxifies cyanide (CN−) by converting it to thiocyanate (SCN−, also known as "rhodanate"). In enzymatology, the common name is listed as thiosulfate sulfurtransferase (). The diagram on the right shows the crystallographically-determined structure of rhodanese.
It catalyzes the following reaction: thiosulfate + cyanide \rightleftharpoons sulfite + thiocyanate