sulfotransferase
Sign in to saveIn biochemistry, sulfotransferases (SULTs) are transferase enzymes that catalyze the transfer of a sulfo group () from a donor molecule to an acceptor alcohol () or amine (). The most common sulfo group donor is 3'-phosphoadenosine-5'-phosphosulfate (PAPS). In the case of alcohol as acceptor, the product is a sulfate ():
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- Subclass of
- transferase
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- topic's main category
- Category:EC 2.8.2
- EC enzyme number
- 2.8.2.-
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In biochemistry, sulfotransferases (SULTs) are transferase enzymes that catalyze the transfer of a sulfo group () from a donor molecule to an acceptor alcohol () or amine (). The most common sulfo group donor is 3'-phosphoadenosine-5'-phosphosulfate (PAPS). In the case of alcohol as acceptor, the product is a sulfate (): \ce{R-SO3-} \ + \ \ce{R'-OH} \quad \xrightarrow[\text{ SULT }]{} \quad \ce{R-H} \ + \ \ce{R'-OSO3-}
whereas an amine leads to a sulfamate (): \ce{R-SO3-} \ + \ \ce{R'-NH2} \quad \xrightarrow[\text{ SULT }]{} \quad \ce{R-H} \ + \ \ce{R'-NHSO3-}
Excerpted from Wikipedia’s “sulfotransferase” article, available under the CC BY-SA 4.0 licence.