RICTOR
Sign in to saveAlso known as AVO3, PIA, hAVO3, RPTOR independent companion of MTOR complex 2
Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene.
Gene data
RICTOR- Name
- RPTOR independent companion of MTOR complex 2
- Type
- protein-coding
- Position
- 38,937,920–39,074,544 (−)
- Aliases
- AVO3, PIA, hAVO3
- Ensembl
- ENSG00000164327
- RefSeq RNA
- NM_001285439.2, NM_001285440.2, NM_001438007.1, NM_001438049.1, NM_001438246.1
- RefSeq protein
- NP_001272368.1, NP_001272369.1, NP_001424936.1, NP_001424978.1, NP_001425175.1
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RPTOR independent companion of MTOR complex 2
- Symbol
- RICTOR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:38,937,920-39,074,544
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~5 min read
Encyclopedic overview
10 sectionsContents
- Structure
- Function
- Regulation
- Degradation
- Interactions
- Clinical relevance
- Cancer
- See also
- References
- Further reading
Rapamycin-insensitive companion of mammalian target of rapamycin (RICTOR) is a protein that in humans is encoded by the RICTOR gene.
RICTOR and mTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth.
Excerpted from Wikipedia’s “RICTOR” article, available under the CC BY-SA 4.0 licence.