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GeneQ18031289· pop 9· linked from 332 articles

Also known as PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K

protein-coding gene in the species Homo sapiens

Gene data

RPS6KB1
Name
ribosomal protein S6 kinase B1
Type
protein-coding
Position
59,893,035–59,963,336 (+)
Aliases
PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
RefSeq RNA
NM_001272042.2, NM_001272043.2, NM_001272044.2, NM_001272060.2, NM_001369669.1
RefSeq protein
NP_001258971.1, NP_001258972.1, NP_001258973.1, NP_001258989.1, NP_001356598.1

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

via MyGene.info

Gene · Ensembl

ribosomal protein S6 kinase B1

Symbol
RPS6KB1
Biotype
Protein coding
Organism
Homo sapiens
Location
17:59,893,035-59,963,336
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein RPS6KB1 PDB 3A60.png
Show 8 more facts
HomoloGene ID
81703
genetic association
multiple sclerosis
found in taxon
Homo sapiens
genomic end
59950574
genomic start
57970447
cytogenetic location
17q23.1
Sources (8)

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