RPS6KB1
Sign in to saveAlso known as PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K
protein-coding gene in the species Homo sapiens
Gene data
RPS6KB1- Name
- ribosomal protein S6 kinase B1
- Type
- protein-coding
- Position
- 59,893,035–59,963,336 (+)
- Aliases
- PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha
- Ensembl
- ENSG00000108443
- RefSeq RNA
- NM_001272042.2, NM_001272043.2, NM_001272044.2, NM_001272060.2, NM_001369669.1
- RefSeq protein
- NP_001258971.1, NP_001258972.1, NP_001258973.1, NP_001258989.1, NP_001356598.1
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ribosomal protein S6 kinase B1
- Symbol
- RPS6KB1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:59,893,035-59,963,336
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI