rifampicin
Sign in to saveRifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium avium complex, leprosy, and Legionnaires' disease. It is almost always used together with other antibiotics with two notable exceptions: when given as a "preferred treatment that is strongly recommended" for latent TB infection; and when used as post-exposure prophylaxis to prevent Haemophilus influenzae type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time,
Research
38,184 papers- Pharmacokinetic interactions with rifampicin : clinical relevance.Clinical pharmacokinetics · 2003
- [Rifampicin-glucocorticoid combinations].La Revue de medecine interne · 1998
- Clinical pharmacokinetics of rifampicin.Clinical pharmacokinetics · 1978
- Rifampicin bioavailability: a review of its pharmacology and the chemotherapeutic necessity for ensuring optimal absorption.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 1999
- Impact of diabetes mellitus on rifampicin's plasma concentration and bioavailability in patients with tuberculosis: A systematic review and meta-analysis study.Therapie · 2023
via PubMed
Article
22 sectionsContents
- Medical uses
- Mycobacteria
- Other bacteria and protozoans
- Viruses
- Pathogen susceptibility
- Primary biliary cholangitis
- Hidradenitis suppurativa
- Adverse effects
- Chemical structure
- Interactions
- Pharmacology
- Mechanism of action
- Mechanism of resistance
- Resistance in tuberculosis
- Pharmacokinetics
- Use in biotechnology
- History
- Society and culture
- Cancer-causing impurities
- Names
- References
- External links
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477172778 | IUPAC_name = (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | image = Rifampicin structure.svg | image_class = skin-invert-image | width = 275 | alt = | image2 = Rifampicin 3D 1i6v.png | image_class2 = bg-transparent | width2 = 225 | alt2 = | USAN = Rifampin
| pronounce = | tradename = Rifadin, others | Drugs.com = | MedlinePlus = a682403 | DailyMedID = Rifampin | pregnancy_AU = C | routes_of_administration = By mouth, Intravenous therapy
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4-Methylpiperazin-1-yl compoundsAntileprotic drugsAnti-tuberculosis drugsCYP1A2 inducersCYP3A4 inducersDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsECHA InfoCard ID from WikidataEnol ethersInfobox drug with local INN variantItalian inventionsNephrotoxins