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pretomanid

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Also known as PA-824

Pretomanid is an antibiotic medication used for the treatment of multi-drug-resistant tuberculosis affecting the lungs. It is generally used together with bedaquiline and linezolid. It is taken by mouth.

Key facts

Drug.legal_EU
Rx-only
Drug.CAS_number
187235-37-6
Drug.UNII
2XOI31YC4N
Drug.PubChem
456199
Drug.image
Pretomanid.svg
Drug.image_class
skin-invert-image
Drug.tradename
Dovprela
Drug.MedlinePlus
a619056
Drug.DailyMedID
Pretomanid
Drug.routes_of_administration
By mouth
Drug.ATC_prefix
J04
Drug.ATC_suffix
AK08
Drug.legal_US
Rx-only
Drug.DrugBank
DB05154
Drug.ChemSpiderID
401693
Drug.KEGG
D10722
Drug.ChEMBL
227875
Drug.synonyms
PA-824

via Wikipedia infobox

Wikidata facts

Mass
359.072905
Show 3 more facts
chemical formula
C₁₄H₁₂F₃N₃O₅
canonical SMILES
C1C(COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
isomeric SMILES
C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
Sources (3)

via Wikidata · CC0

~6 min read

Article

8 sections
Contents
  • Medical uses
  • Mechanism of action
  • History
  • Discovery and pre-clinical development
  • Society and culture
  • Legal status
  • Names
  • References

{{Infobox drug | image = Pretomanid.svg | image_class = skin-invert-image | alt = | caption =

| pronounce = | tradename = Dovprela | Drugs.com = | MedlinePlus = a619056 | DailyMedID = Pretomanid | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | class = | ATC_prefix = J04 | ATC_suffix = AK08

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