rifamycin
Sign in to saveThe rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections.
Key facts
- Drug.StdInChI
- 1S/C37H47NO12/c1-16-11-10-12-17(2)36(46)38-23-15-24(40)26-27(32(23)44)31(43)21(6)34-28(26)35(45)37(8,50-34)48-14-13-25(47-9)18(3)33(49-22(7)39)20(5)30(42)19(4)29(16)41/h10-16,18-20,25,29-30,33,40-44H,1-9H3,(H,38,46)/b11-10+,14-13+,17-12-/t16-,18+,19+,20+,25-,29-,30+,33+,37-/m0/s1
- Drug.StdInChIKey
- HJYYPODYNSCCOU-ODRIEIDWSA-N
- Drug.image
- Rifamycin SV.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Rifamycin SV stick 6BEB.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Aemcolo
- Drug.MedlinePlus
- a619010
- Drug.DailyMedID
- Rifamycin
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- A07
- Drug.ATC_suffix
- AA13
- Drug.legal_US
- Rx-only
- Drug.index2_label
- as salt
- Drug.CAS_number
- 6998-60-3
- Drug.PubChem
- 6324616
- Drug.DrugBank
- DB11753
- Drug.ChemSpiderID
- 16735998
via Wikipedia infobox
Article
9 sectionsContents
- Bacterium
- First drugs
- Clinical trials
- Mechanism of action
- Biosynthesis
- Derivatives
- Available rifamycins
- References
- Further reading
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections.
The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances.