RIPK2
Sign in to saveAlso known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor interacting serine/threonine kinase 2
Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.
Gene data
RIPK2- Name
- receptor interacting serine/threonine kinase 2
- Type
- protein-coding
- Position
- 89,757,733–89,791,847 (+)
- Aliases
- CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
- Ensembl
- ENSG00000104312
- RefSeq RNA
- NM_001375360.1, NM_003821.6, XM_011517357.3, XM_054361439.1
- RefSeq protein
- NP_001362289.1, NP_003812.1, XP_011515659.1, XP_054217414.1
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
receptor interacting serine/threonine kinase 2
- Symbol
- RIPK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:89,757,733-89,791,847
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-κB and inducer of apoptosis in response to various stimuli.
Excerpted from Wikipedia’s “RIPK2” article, available under the CC BY-SA 4.0 licence.