RIPK2
Sign in to saveAlso known as CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor interacting serine/threonine kinase 2
Gen der Spezies Homo sapiens
Gene data
RIPK2- Name
- receptor interacting serine/threonine kinase 2
- Type
- protein-coding
- Position
- 89,757,733–89,791,847 (+)
- Aliases
- CARD3, CARDIAK, CCK, GIG30, RICK, RIP2
- Ensembl
- ENSG00000104312
- RefSeq RNA
- NM_001375360.1, NM_003821.6, XM_011517357.3, XM_054361439.1
- RefSeq protein
- NP_001362289.1, NP_003812.1, XP_011515659.1, XP_054217414.1
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
NOD-like receptor signaling pathway - Homo sapiens (human)Neurotrophin signaling pathway - Homo sapiens (human)Shigellosis - Homo sapiens (human)Salmonella infection - Homo sapiens (human)Tuberculosis - Homo sapiens (human)Cytokine Signaling in Immune systemAdaptive Immune SystemSignal TransductionDiseaseToll Like Receptor 4 (TLR4) Cascade
via MyGene.info
Gene · Ensembl
receptor interacting serine/threonine kinase 2
- Symbol
- RIPK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:89,757,733-89,791,847
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 10 more facts
- cytogenetic location
- 8q21.3
- HomoloGene ID
- 37856
- genetic association
- leprosy
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8767
- genomic end
- 89791064
- genomic start
- 89757806
- chromosome
- human chromosome 8
- expressed in
- oocyte
- Commons category
- RIPK2
via Wikidata · CC0