RSPO2
Sign in to saveAlso known as CRISTIN2, R-spondin 2, TETAMS2, HHRRD
protein-coding gene in the species Homo sapiens
Gene data
RSPO2- Name
- R-spondin 2
- Type
- protein-coding
- Aliases
- CRISTIN2, HHRRD, TETAMS2
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
via MyGene.info
Gene · Ensembl
R-spondin 2
- Symbol
- RSPO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:107,899,316-108,083,791
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 18235
- exact match
- identifiers.org/ncbigene/340419
- genomic end
- 108083642
- genomic start
- 108911544
- chromosome
- human chromosome 8
- cytogenetic location
- 8q23.1
- expressed in
- cingulate gyrus
Sources (3)
via Wikidata · CC0