RSPO2
Sign in to saveAlso known as CRISTIN2, R-spondin 2, TETAMS2, HHRRD
protein-coding gene in the species Homo sapiens
Gene data
RSPO2- Name
- R-spondin 2
- Type
- protein-coding
- Aliases
- CRISTIN2, HHRRD, TETAMS2
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 18235
- exact match
- identifiers.org/ncbigene/340419
- genomic end
- 108083642
- genomic start
- 108911544
- cytogenetic location
- 8q23.1
Sources (3)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 8
Entity
Ensembl genome database project
Entity
lung
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
public domain
Entity
digital object identifier
Entity
bibcode
Entity
human genome
Entity
genetic disease
Entity
Q229883
Entity
base pair
Entity
locus
Entity
gene expression
Entity
limb
Entity
Online Mendelian Inheritance in Man
Entity
ectoderm
Entity