saccharopine
Sign in to saveAlso known as epsilon-N-(L-Glutar-2-yl)-L-lysine, N-[(S)-5-Amino-5-carboxypentyl]-L-glutamic acid, L-Saccharopin, N6-(L-1,3-Dicarboxypropyl)-L-lysine, N-(5-Amino-5-carboxypentyl)-L-glutamic acid, (S)-N-(5-amino-5-carboxypentyl)-L-Glutamic acid, N(6)-(L-1,3-Dicarboxypropyl)-L-lysine, N-[(5S)-5-Amino-5-carboxypentyl]-L-Glutamic acid
Saccharopine is an intermediate in the metabolism of amino acid lysine. It is a precursor of lysine in the alpha-aminoadipate pathway which occurs in fungi and euglenids. In mammals and seed plants saccharopine is an intermediate in the degradation of lysine, formed by condensation of lysine and alpha-ketoglutarate.
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Encyclopedic overview
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- Biochemical reactions
- Pathology
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{{chembox | ImageFile = Saccharopine.svg | ImageFile_Ref = | ImageName = Stereo, skeletal formula of saccharopine ((2S)-2-{[(5S)-5-aminopentyl]amino}) | IUPACName = 2-[(5-Amino-5-carboxypentyl)amino]pentanedioic acid | Section1 = | Section2 = | Section3 = }}
Saccharopine is an intermediate in the metabolism of amino acid lysine. It is a precursor of lysine in the alpha-aminoadipate pathway which occurs in fungi and euglenids. In mammals and seed plants saccharopine is an intermediate in the degradation of lysine, formed by condensation of lysine and alpha-ketoglutarate.
Excerpted from Wikipedia’s “saccharopine” article, available under the CC BY-SA 4.0 licence.