salinomycin
Sign in to saveSalinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. It is widely researched for its anticancer stem cell properties.
Chemical data
- Formula
- C42H70O11
- Molecular weight
- 751 g/mol
- IUPAC name
- (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
via PubChem
Wikidata facts
- Mass
- +750.49181306
via Wikidata · CC0
Article
7 sectionsContents
- Antibacterial activity
- Cancer research
- Pre-clinical
- Use in agriculture
- Biosynthesis
- See also
- References
Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. It is widely researched for its anticancer stem cell properties.
Salinomycin is also known to isomerise in solution. This unique property complicates its structural elucidation studies in areas such as analytical chemistry and pharmaceutical development. Mass spectrometry is the primary research technique in the analysis of polyether ionophores such as salinomycin. Different salinomycin isomers can generate unique sets of product ions in the mass spectrometer. A complete structural characterisation and fragmentation pathways for salinomycin and its isomers is important in understanding its fragmentation behaviour and provides firm ground for its future clinical drug discovery research.