SASH1
Sign in to saveAlso known as SH3D6A, dJ323M4, dJ323M4.1, SAM and SH3 domain containing 1, DUH1, CAPOK
SAM and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SASH1 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to SASH1, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 7 Wikipedia language editions.
Gene data
SASH1- Name
- SAM and SH3 domain containing 1
- Type
- protein-coding
- Position
- 148,272,304–148,552,044 (+)
- Aliases
- CAPOK, DUH, DUH1, SH3D6A, dJ323M4.1
- Ensembl
- ENSG00000111961
- RefSeq RNA
- NM_001346505.2, NM_001346506.2, NM_001346507.2, NM_001346508.2, NM_001346509.2
- RefSeq protein
- NP_001333434.1, NP_001333435.1, NP_001333436.1, NP_001333437.1, NP_001333438.1
This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
SAM and SH3 domain containing 1
- Symbol
- SASH1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:148,272,304-148,552,044
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SASH1 PDB 2dl0.png
Show 7 more facts
- HomoloGene ID
- 69182
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23328
- genomic end
- 148552044
- genomic start
- 148593440
- chromosome
- human chromosome 6
- cytogenetic location
- 6q24.3-q25.1
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
SAM and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SASH1 gene.
==References==
Excerpted from Wikipedia’s “SASH1” article, available under the CC BY-SA 4.0 licence.