SDHD

Name

succinate dehydrogenase complex subunit D

Type

protein-coding

Position

112,086,361–112,120,016 (+)

Aliases

CBT1, CII-4, CWS3, MC2DN3, PGL, PGL1, PPGL1, QPs3, SDH4, cybS

Ensembl

ENSG00000204370

RefSeq RNA

NM_001276503.2, NM_001276504.2, NM_001276506.2, NM_003002.4, NR_077060.2

RefSeq protein

NP_001263432.1, NP_001263433.1, NP_001263435.1, NP_002993.1

This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013].

via MyGene.info

Gene · Ensembl

succinate dehydrogenase complex subunit D

Symbol

SDHD

Biotype

Protein coding

Organism

Homo sapiens

Location

11:112,086,361-112,120,016

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

SuccDeh.svg

via Wikidata · CC0