simethicone

Also known as simeticone

Simeticone (INN), also known as simethicone (USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.

In the Vinony graph

Within Vinony's link graph, simethicone is referenced by 169 other articles, and connects out to combination drug, pinaverium and pipenzolate bromide.

Vinony files it under Antiflatulents, Chemicals that do not have a ChemSpider ID assigned and Digestive system.

Its subject is documented across 23 Wikipedia language editions.

Key facts

Drug.molecular_weight: Variable
Drug.Verifiedfields: changed
Drug.verifiedrevid: 417768970
Drug.IUPAC_name: Poly(dimethylsiloxane), silicon dioxide
Drug.image: Simethicone structure.svg
Drug.image_class: skin-invert-image
Drug.tradename: Infacol, Wind-eze, WindSetlers, others
Drug.USAN: Simethicone
Drug.pregnancy_category: C
Drug.legal_US: OTC
Drug.routes_of_administration: Oral
Drug.bioavailability: None
Drug.protein_bound: 0%
Drug.metabolism: Not metabolized
Drug.elimination_half life: N/A
Drug.excretion: Feces
Drug.CAS_number: 8050-81-5
Drug.ATC_prefix: A03

via Wikipedia infobox

Chemical data

Formula: C6H18O4Si3
Molecular weight: 238.46 g/mol
IUPAC name: dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
InChIKey: AMTWCFIAVKBGOD-UHFFFAOYSA-N
Polar surface area: 52.6 Å²
H-bond donors: 0
H-bond acceptors: 4
Formal charge: 0

via PubChem

Research

620 papers

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 238.05128864600005

Show 3 more facts

chemical formula: C₆H₁₈O₄Si₃
canonical SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
therapeutic area: functional gastrointestinal disorder

Sources (3)

via Wikidata · CC0

~6 min read

Encyclopedic overview

6 sections

Contents

Medical uses
Side effects
Pharmacology
Chemistry
Names
References

Simeticone (INN), also known as simethicone (USAN), is an anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas.

==Medical uses== thumb|Simethicone tablets Simethicone is used to relieve the symptoms of excessive gas in the gastrointestinal tract, namely bloating, burping, and flatulence. While there is a lack of conclusive evidence that simethicone is effective for this use,⁣ studies have shown that it can relieve symptoms of functional dyspepsia and functional bloating.

Excerpted from Wikipedia’s “simethicone” article, available under the CC BY-SA 4.0 licence.