anticholinergic
Sign in to saveAlso known as anticholinergic agent, cholinergic antagonist, Cholinergic Receptor Antagonists, Acetylcholine Antagonists, Cholinolytics, Cholinergic-Blocking Agents, cholinergic blocking drug, parasympatholytic drug
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system.
Research
106,062 papers- Anticholinergic Medication Burden-Associated Cognitive Impairment in Schizophrenia.The American journal of psychiatry · 2021
- An Evidence-Based Update on Anticholinergic Use for Drug-Induced Movement Disorders.CNS drugs · 2024
- Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults.The Cochrane database of systematic reviews · 2023
- Anticholinergic bronchodilators.Respiratory care clinics of North America · 1999
- Anticholinergic medication for antipsychotic-induced tardive dyskinesia.The Cochrane database of systematic reviews · 2018
via PubMed
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Encyclopedic overview
13 sectionsContents
- Medical uses
- Physiological effects
- Cognitive and physical decline
- Side effects
- Toxicity
- Dementia
- Pharmacology
- Examples
- Antidotes
- Psychoactive uses
- Plant sources
- Use as a deterrent
- References
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system.
These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, sweat glands, and many other parts of the body.
Excerpted from Wikipedia’s “anticholinergic” article, available under the CC BY-SA 4.0 licence.