File:Child_with_Smallpox_Bangladesh.jpg · Wikimedia Commons · See Wikimedia Commons

EntityQ12214· pop 143· linked from 4,564 articles

天花

Also known as Red Plague, pox, speckled monster

天花病毒引起的傳染病

OverviewAI-generated

Smallpox is a disease with an incubation period in humans ranging from a minimum of 10 days to a maximum of 17 days. It is classified under ICD-9-CM codes 050.9 and 050, and is identified by the ICPC 2 ID A76 and the NCI Thesaurus ID C35027. The condition is categorized in the Commons category "Smallpox."

The disease was dissolved, abolished, or demolished in 1978. It is referenced by 4,564 other encyclopedia articles. There are 12,781 PubMed entries associated with the query "smallpox." The topic is described at a URL provided by the CDC Taiwan and is linked to a WordLift URL. The title for the subject in some sources is "天花 - 衛生福利部疾病管制署."

Synthesized by Vinony from 17 facts across 4 sources: Wikidata, Firecrawl, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Medical condition.synonyms: variola, variola vera, pox, red plague
Medical condition.image: Child with Smallpox Bangladesh.jpg
Medical condition.caption: A child with smallpox in Bangladesh in 1973. The bumps filled with thick fluid and a depression or dimple in the center are characteristic.
Medical condition.field: Infectious disease
Medical condition.complications: Scarring of the skin, blindness
Medical condition.onset: 1 to 3 weeks following exposure
Medical condition.duration: About 4 weeks
Medical condition.causes: variola major virus, variola minor virus (spread between people)
Medical condition.diagnosis: Based on symptoms and confirmed by PCR
Medical condition.differential: Chickenpox, impetigo, molluscum contagiosum, mpox
Medical condition.prevention: Smallpox vaccine
Medical condition.treatment: Supportive care
Medical condition.medication: Brincidofovir
Medical condition.prognosis: 30% risk of death
Medical condition.frequency: Eradicated (last naturally occurring case in 1977)

via Wikipedia infobox

Research

12,781 papers

Smallpox in the Post-Eradication Era.ReviewViruses · 2020Meyer H, Ehmann R, Smith GLDOI: 10.3390/v12020138
Smallpox, Monkeypox and Other Human Orthopoxvirus Infections.ReviewViruses · 2022Shchelkunova GA, Shchelkunov SNDOI: 10.3390/v15010103
Smallpox.JAMA · 2022DOI: 10.1001/jama.2021.17055
Smallpox and monkeypox: Looking back and looking ahead.ReviewCleveland Clinic journal of medicine · 2023Sossai P, Staiti D, Cannas M et al.DOI: 10.3949/ccjm.90a.22067
Treatment and Vaccination for Smallpox and Monkeypox.ReviewAdvances in experimental medicine and biology · 2024Saalbach KPDOI: 10.1007/978-3-031-57165-7_19
[Smallpox].ReviewNederlands tijdschrift voor tandheelkunde · 2003Bol P
[We should be prepared to smallpox re-emergence.].ReviewVoprosy virusologii · 2019Shchelkunov SN, Shchelkunova GADOI: 10.36233/0507-4088-2019-64-5-206-214
The rediscovery of smallpox.ReviewClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2014Thèves C, Biagini P, Crubézy EDOI: 10.1111/1469-0691.12536

via PubMed

Described at

cdc.gov.tw →

Link to a page describing this subject · not written by Vinony

Wikidata facts

Instance of: symptom or sign
Subclass of: manner of death
Image: Child with Smallpox Bangladesh.jpg

Show 20 more facts

medical examination: electron microscope
afflicts: human
has cause: Variola virus (vaccinia)
Commons category: Smallpox
topic's main category: Category:Smallpox
NCI Thesaurus ID: C35027
health specialty: infectious diseases
ICPC 2 ID: A76
minimal incubation period in humans: 10
symptoms and signs: scar
maximal incubation period in humans: 12
drug or therapy used for treatment: tecovirimat
on focus list of Wikimedia project: Wikipedia:Vital articles/Level/4
ICD-9-CM: 050
WordLift URL: data.medicalrecords.com/medicalrecords/healthwise/smallpox
dissolved, abolished or demolished date: 1978-00-00
exact match: identifiers.org/doid/DOID:8736
described at URL: www.cdc.gov.tw/Disease/SubIndex/r-efSTx60KilIEf_MlwknA
has natural reservoir: human
P8168: associative array

Sources (10)

via Wikidata · CC0

Article · 中文

天花（英語：Smallpox）是一種由天花病毒引起之人類傳染病。患者一般在染病後的12天內，出現包括發燒、肌肉疼痛、頭痛等近似普通感冒的症狀。幾天後，口咽部分的粘膜會長出紅點，身體多處地方亦會長出皮疹（以臉部居多）。天花病毒共有兩類：主天花病毒及次天花病毒。根據患者的病情發展，由前者引發之天花又被劃分為四種形式：典型、惡性、出血型、緩和型。其中，多數未曾接種疫苗者均會出現典型天花的症狀。次天花病毒引起之病變程度比上述四種都要溫和，但卻非常罕見。天花主要透過空氣傳播。患者的呼吸道與皮膚皰疹分泌物均載有病毒，故避免與其近距離接觸可減低患病的風險。多種痘病毒疾病的病癥均與天花的如出一轍。專家需利用進行病毒培植以確定天花病毒的存在，聚合酶鏈式反應及限制性片段長度多態性測試可提供更多病毒的細節。接種天花疫苗為預防此病的最佳方法。目前並沒有認可的抗天花藥物。一旦出現確診病例，醫護人員會為病人注射疫苗提升免疫保護，有時亦會配以舒緩性療法加大療效。天花病毒不會造成慢性或復發性感染，但會導致各類併發症或後遺症（如失明）。不同類型的天花所引發的病死率不一；最為常見的典型天花約奪取了三成病患者的性命。古埃及或許為天花的起源地。已死去逾三千年的法老拉美西斯五世可能是史上已知最早的天花病人，專家在其木乃伊身上找到了明顯的膿皰痕跡。早期的印度及中國文獻亦有記載這種疾病。在隨後的漫長歲月裡，天花於世界多個地方展開大流行，並奪取了無數人類的性命（尤其是兒童）。歷史上，有不少國家的君王及著名人物均染上過天花。19至20世紀期間，多番的防疫行動減低了此病對群眾的威脅。最終，世界衛生組織於1980年正式宣布撲滅天花，使之成為首個於世上絕跡的人類傳染病。

Abstract from DBpedia / Wikipedia · CC BY-SA