SMARCA2

Name

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

Type

protein-coding

Position

1,980,290–2,193,624 (+)

Aliases

BAF190, BIS, BRM, NCBRS, SAMRCA2, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p

Ensembl

ENSG00000080503

RefSeq RNA

NM_001289396.2, NM_001289397.2, NM_001289398.2, NM_001289399.2, NM_001289400.2

RefSeq protein

NP_001276325.1, NP_001276326.1, NP_001276327.1, NP_001276328.1, NP_001276329.1

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014].

via MyGene.info

Gene · Ensembl

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2

Symbol

SMARCA2

Biotype

Protein coding

Organism

Homo sapiens

Location

9:1,980,290-2,193,624

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein SMARCA2 PDB 2dat.png

via Wikidata · CC0