Also known as ASV, SRC1, c-SRC, p60-Src, SRC proto-oncogene, non-receptor tyrosine kinase, THC6
protein-coding gene in the species Homo sapiens
Gene data
SRC- Name
- SRC proto-oncogene, non-receptor tyrosine kinase
- Type
- protein-coding
- Position
- 37,344,673–37,406,050 (+)
- Aliases
- ASV, SRC1, THC6, c-SRC, p60-Src
- Ensembl
- ENSG00000197122
- RefSeq RNA
- NM_005417.5, NM_198291.3, XM_017028026.2, XM_047440396.1, XM_047440397.1
- RefSeq protein
- NP_005408.1, NP_938033.1, XP_016883515.1, XP_047296352.1, XP_047296353.1
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SRC proto-oncogene, non-receptor tyrosine kinase
- Symbol
- SRC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:37,344,673-37,406,050
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI