SRC激酶

Name

SRC proto-oncogene, non-receptor tyrosine kinase

Type

protein-coding

Position

37,344,673–37,406,050 (+)

Aliases

ASV, SRC1, THC6, c-SRC, p60-Src

Ensembl

ENSG00000197122

RefSeq RNA

NM_005417.5, NM_198291.3, XM_017028026.2, XM_047440396.1, XM_047440397.1

RefSeq protein

NP_005408.1, NP_938033.1, XP_016883515.1, XP_047296352.1, XP_047296353.1

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

SRC proto-oncogene, non-receptor tyrosine kinase

Symbol

SRC

Biotype

Protein coding

Organism

Homo sapiens

Location

20:37,344,673-37,406,050

Strand

Forward (+)

Assembly

GRCh38