sulfonamide
Sign in to saveAlso known as sulphonamide, sulfonamides, sulphonamides, sulfonamide compound, sulfonic acid amide
thumb|200px|The structure of the sulfonamide group
Research
162,940 papers- [«Sulfonamide allergy» - which drugs must patients avoid?].Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 2016
- Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2023
- Sulfonamide-Pyrazole derivatives as next-generation Cyclooxygenase-2 enzyme inhibitors: From molecular design to in vivo efficacy.International journal of biological macromolecules · 2025
- Coumarin-Based Sulfonamide Derivatives as Potential DPP-IV Inhibitors: Pre-ADME Analysis, Toxicity Profile, Computational Analysis, and In Vitro Enzyme Assay.Molecules (Basel, Switzerland) · 2023
- Examination of sulfonamide-based inhibitors of MMP3 using the conditioned media of invasive glioma cells.Journal of enzyme inhibition and medicinal chemistry · 2020
via PubMed
Wikidata facts
Show 4 more facts
- CXSMILES
- [*]S(=O)(=O)N([*])[*] |$R1;;;;;R2;R3$|
- SMARTS notation
- *-[#7](-*)S(*)(=O)=O
- Commons category
- Sulfonamides
- canonical SMILES
- [*]S(=O)(=O)N([*])[*]
Sources (3)
via Wikidata · CC0
~4 min read
Article
6 sectionsContents
- Synthesis and reactions
- Sultams<span class="anchor" id="Sultams"></span>
- Disulfonimides
- See also
- References
- Further reading
thumb|200px|The structure of the sulfonamide group
In organic chemistry, the sulfonamide functional group (also spelled sulphonamide) is an organosulfur group with the structure . It consists of a sulfonyl group () connected to an amine group (). Relatively speaking this group is unreactive. Because of the rigidity of the functional group, sulfonamides are typically crystalline; for this reason, the formation of a sulfonamide is a classic method to convert an amine into a crystalline derivative which can be identified by its melting point. Many important drugs contain the sulfonamide group.