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anticoagulant

File:Coagulation_Cascade_and_Major_Classes_of_Anticoagulants.png · Wikimedia Commons · See Wikimedia Commons

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anticoagulant

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Also known as anticoagulant drug, anticoagulant agent, anticoagulants

An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

Key facts

Drug class.Name
Anticoagulant
Drug class.Image
Coagulation Cascade and Major Classes of Anticoagulants.png
Drug class.ImageClass
skin-invert-image
Drug class.Caption
Coagulation cascade and major classes of anticoagulants
Drug class.ATC_prefix
B01
Drug class.MeshID
D00534-class

via Wikipedia infobox

~26 min read

Encyclopedic overview

22 sections
Contents
  • Medical uses
  • Adverse effects
  • Interactions
  • Types
  • Heparin and derivative substances
  • Low molecular weight heparin (LMWH)
  • Synthetic pentasaccharide inhibitors of factor Xa
  • <span class="anchor" id="Direct oral anticoagulants"></span> Direct oral
  • Direct factor Xa inhibitors
  • Direct thrombin inhibitors
  • Relevance to dental treatments
  • Antithrombin protein therapeutics
  • Other
  • Reversal agents
  • Coagulation inhibitor measurement
  • Laboratory use
  • Dental considerations for long-term users
  • Research
  • Utilization
  • See also
  • References
  • External links

An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

As a class of medications, anticoagulants are used in therapy for thrombotic disorders. Oral anticoagulants (OACs) are taken by many people in pill or tablet form, and various intravenous anticoagulant dosage forms are used in hospitals. Some anticoagulants are used in medical equipment, such as sample tubes, blood transfusion bags, heart–lung machines, and dialysis equipment. One of the first anticoagulants, warfarin, was initially approved as a rodenticide.

Excerpted from Wikipedia’s “anticoagulant” article, available under the CC BY-SA 4.0 licence.