File:Thymol2.svg · Wikimedia Commons · See Wikimedia Commons
thymol
Sign in to saveAlso known as 3-p-cymenol, 6-isopropyl-m-cresol, 2-isopropyl-5-methylphenol, 1-hydroxy-5-methyl-2-isopropylbenzene, 5-methyl-2-isopropylphenol, 6-isopropyl-3-methylphenol, isopropyl cresol, 6-isopropyl-p-cresol
Thymol (also known as 2-isopropyl-5-methylphenol, IPMP), , is a monoterpenoid, phenol derivative of p-cymene, isomeric with carvacrol. It occurs naturally in oil of thyme and is extracted from Thymus vulgaris (common thyme), ajwain, and various other plants, as a white crystalline substance with a pleasant aromatic odor.
OverviewAI-generated
Thymol is a chemical compound with the formula C₁₀H₁₄O. Its IUPAC name is 5-methyl-2-propan-2-ylphenol. The substance has a mass of 150.104 and a density of 0.97. It exhibits a melting point of 51.5 and a boiling point of 233. The refractive index is 1.5227, and the vapor pressure is 100. Solubility is listed as 1.
Chemical properties include a charge of 0, one hydrogen bond donor, and one hydrogen bond acceptor. The topological polar surface area is 20.2, and the xlogp value is 3.3. The canonical SMILES representation is CC1=CC(=C(C=C1)C(C)C)O.
In scientific literature, there are 8153 PubMed entries associated with the query "thymol". The subject is referenced by 846 other encyclopedia articles.
Synthesized by Vinony from 24 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C10H14O
- Molecular weight
- 150.22 g/mol
- IUPAC name
- 5-methyl-2-propan-2-ylphenol
- SMILES
- CC1=CC(=C(C=C1)C(C)C)O
- InChIKey
- MGSRCZKZVOBKFT-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 20.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Research
8,153 papers- Thymol, thyme, and other plant sources: Health and potential uses.Phytotherapy research : PTR · 2018
- Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
- Thymol and carvacrol supplementation in poultry health and performance.Veterinary medicine and science · 2022
- Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics.Molecules (Basel, Switzerland) · 2024
- Effects of Carvacrol, Thymol and essential oils containing such monoterpenes on wound healing: a systematic review.The Journal of pharmacy and pharmacology · 2019
via PubMed
~5 min read
Encyclopedic overview
11 sectionsContents
- Chemical synthesis
- History
- Extraction
- Uses
- List of plants that contain thymol
- Toxicology and environmental impacts
- Environmental breakdown and use as a pesticide
- Compendial status
- See also
- Notes and references
- External links
Thymol (also known as 2-isopropyl-5-methylphenol, IPMP), , is a monoterpenoid, phenol derivative of p-cymene, isomeric with carvacrol. It occurs naturally in oil of thyme and is extracted from Thymus vulgaris (common thyme), ajwain, and various other plants, as a white crystalline substance with a pleasant aromatic odor.
Thymol provides the distinctive flavor of the culinary herb thyme, also produced from T. vulgaris. Thymol is only slightly soluble in water at neutral pH, but due to deprotonation of the phenol, it is highly soluble in alcohols, other organic solvents, and strongly alkaline aqueous solutions.
Excerpted from Wikipedia’s “thymol” article, available under the CC BY-SA 4.0 licence.