Structure via PubChem · Public domain (PubChem)
bromazepam
Sign in to saveAlso known as Ro-53350, Lectopam, Bromazepamum
Bromazepam, sold under many brand names, is a benzodiazepine. It is mainly an anti-anxiety agent with similar side effects to diazepam. In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery. Bromazepam typically comes in doses of 1.5 mg, 3 mg and 6 mg tablets.
Key facts
- Drug.image_class
- skin-invert-image
- Drug.width
- 222
- Drug.image2
- Bromazepam-from-xtal-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Lexotan, Lexilium, others
- Drug.DailyMedID
- Bromazepam
- Drug.addiction_liability
- High
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- BA08
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- /Appendix D, clause 5 (Benzodiazepine derivatives); Appendix K, clause 1
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.legal_DE
- Rx-only/Anlage III
- Drug.legal_UK
- Class C
- Drug.legal_US
- Schedule IV
- Drug.bioavailability
- 84%
via Wikipedia infobox
Chemical data
- Formula
- C14H10BrN3O
- Molecular weight
- 316.15 g/mol
- IUPAC name
- 7-bromo-5-pyridin-2-yl-1,3-dihydro-1,4-benzodiazepin-2-one
- SMILES
- C1C(=O)NC2=C(C=C(C=C2)Br)C(=N1)C3=CC=CC=N3
- InChIKey
- VMIYHDSEFNYJSL-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 54.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
650 papers- Bromazepam.2006
- Bromazepam-induced dystonia.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 1992
- Megadose bromazepam dependence.Psychiatria Danubina · 2016
- Bromazepam increases the error of the time interval judgments and modulates the EEG alpha asymmetry during time estimation.Consciousness and cognition · 2022
- Chemical gastritis after chronic bromazepam intake: a case report.BMC gastroenterology · 2010
via PubMed
Wikidata facts
- Mass
- 315.000724
Show 5 more facts
- MCN code
- 2933.33.22
- chemical formula
- C₁₄H₁₀BrN₃O
- canonical SMILES
- C1C(=O)NC2=C(C=C(C=C2)Br)C(=N1)C3=CC=CC=N3
- Commons category
- Bromazepam
- defined daily dose
- 10
via Wikidata · CC0
~12 min read
Article
17 sectionsContents
- Medical uses
- Pharmacology
- Pharmacokinetics
- Side-effects
- Frequency and seriousness of adverse effects
- Tolerance, dependence and withdrawal
- Overdose
- Contraindications
- Special populations
- Interactions
- Society and culture
- Drug misuse
- Brand names
- Legal status
- Synthesis
- References
- External links
Bromazepam, sold under many brand names, is a benzodiazepine. It is mainly an anti-anxiety agent with similar side effects to diazepam. In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery. Bromazepam typically comes in doses of 1.5 mg, 3 mg and 6 mg tablets.
It was patented in 1961 by Roche and approved for medical use in 1974.