TLE2
Sign in to saveAlso known as ESG, ESG2, GRG2, transducin like enhancer of split 2, TLE family member 2, transcriptional corepressor
gène de l'espèce Homo sapiens
Gene data
TLE2- Name
- TLE family member 2, transcriptional corepressor
- Type
- protein-coding
- Position
- 2,997,632–3,047,635 (−)
- Aliases
- ESG, ESG2, GRG2
- Ensembl
- ENSG00000065717
- RefSeq RNA
- NM_001144761.2, NM_001144762.2, NM_001300846.2, NM_003260.5, XM_006722864.3
- RefSeq protein
- NP_001138233.1, NP_001138234.1, NP_001287775.1, NP_003251.2, XP_006722927.1
Enables transcription corepressor activity. Involved in negative regulation of canonical Wnt signaling pathway and negative regulation of transcription, DNA-templated. Located in focal adhesion and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
Wnt signaling pathway - Homo sapiens (human)Notch signaling pathway - Homo sapiens (human)Signaling by NOTCHSignal TransductionSignal TransductionDegradation of beta-catenin by the destruction complexDegradation of beta-catenin by the destruction complexSignaling by WNTSignaling by WNTSignaling by NOTCH1
via MyGene.info
Gene · Ensembl
TLE family member 2, transcriptional corepressor
- Symbol
- TLE2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:2,997,632-3,047,635
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 20693
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7089
- genomic end
- 3047633
- genomic start
- 2997639
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.3
- expressed in
- sural nerve
Sources (4)
via Wikidata · CC0
Article · Français
La protéine de renforcement de type transductine 2 est une protéine qui est codée par le gène TLE2 chez l’homme.
Abstract from DBpedia / Wikipedia · CC BY-SA