TP73

Name

tumor protein p73

Type

protein-coding

Position

3,652,307–3,736,201 (+)

Aliases

CILD47, P73

Ensembl

ENSG00000078900

RefSeq RNA

NM_001126240.3, NM_001126241.3, NM_001126242.3, NM_001204184.2, NM_001204185.2

RefSeq protein

NP_001119712.1, NP_001119713.1, NP_001119714.1, NP_001191113.1, NP_001191114.1

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

via MyGene.info

Gene · Ensembl

tumor protein p73

Symbol

TP73

Biotype

Protein coding

Organism

Homo sapiens

Location

1:3,652,307-3,736,201

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein TP73 PDB 1cok.png

via Wikidata · CC0