ZBTB20
Sign in to saveAlso known as DPZF, HOF, ODA-8S, ZNF288, PRIMS, zinc finger and BTB domain containing 20
Zinc finger and BTB domain-containing protein 20 is a protein that in humans is encoded by the ZBTB20 gene.
In the Vinony graph
Within Vinony's link graph, ZBTB20 is referenced by 812 other articles, and connects out to Q180686, human chromosome 3 and homeobox.
Vinony files it under Genes on human chromosome 3 and Transcription factors.
Its subject is documented across 5 Wikipedia language editions.
Gene data
ZBTB20- Name
- zinc finger and BTB domain containing 20
- Type
- protein-coding
- Position
- 114,314,500–115,147,356 (−)
- Aliases
- DPZF, HOF, ODA-8S, PRIMS, ZNF288
- Ensembl
- ENSG00000181722
- RefSeq RNA
- NM_001164342.2, NM_001164343.2, NM_001164344.4, NM_001164345.4, NM_001164346.2
- RefSeq protein
- NP_001157814.1, NP_001157815.1, NP_001157816.1, NP_001157817.1, NP_001157818.1
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
zinc finger and BTB domain containing 20
- Symbol
- ZBTB20
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:114,314,500-115,147,356
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9226
- exact match
- identifiers.org/ncbigene/26137
- cytogenetic location
- 3q13.31
- genomic end
- 115147288
- genomic start
- 114314500
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Zinc finger and BTB domain-containing protein 20 is a protein that in humans is encoded by the ZBTB20 gene.
A mutation in a ZBTB20 gene causes Primrose syndrome.
Excerpted from Wikipedia’s “ZBTB20” article, available under the CC BY-SA 4.0 licence.