tribenuron-methyl

Tribenuron in the form of tribenuron-methyl is a sulfonylurea herbicide. Its mode of action is the inhibition of acetolactate synthase, Group 2 / Group B of the Herbicide Resistance Action Committee's classification scheme.

==Chemistry== In the 1970s, chemists at DuPont worked extensively on sulfonylurea herbicides, following the invention of this class of herbicides by George Levitt which had led to the commercialisation of chlorsulfuron. Tribenuron (the carboxylic acid) and its methyl ester were first disclosed in general terms in one of Levitt's patents and subsequently the ester was subject to further patenting and selected for development under the code name DPX L5300. In the final step of its synthesis, 2-methoxycarbonylbenzenesulfonyl isocyanate was condensed with 2-methylamino-4-methoxy-6-methyl-1,3,5-triazine to form the sulfonylurea product. 650px ==Mode of action== Tribenuron is an herbicide that acts as an acetolactate synthase inhibitor. For the purposes of herbicide resistance management, the Herbicide Resistance Action Committee has placed it in group 2 (legacy HRAC Group B). ==Applications== thumb|US Geological Survey estimate of tribenuron methyl use in the USA to 2018 Tribenuron has a broad spectrum of activity on commercially important broadleaf weeds and grasses but at the recommended use rate it is safe to important crops such as wheat. When introduced by DuPont, its recommended application rate was . The estimated use in US agriculture is mapped by the US Geological Service and shows that from 1992 to 2018, up to were applied each year. The compound is used mainly in wheat but also in pasture. ==Physicochemistry== In a clay-water suspension, tribenuron has increased sorption with decreasing pH and even more so with suspended load.