tylosin
Sign in to saveAlso known as Tylosin A, Tylocine, Tylan
Tylosin is a macrolide antibiotic and bacteriostatic feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. It is found naturally as a fermentation product of Streptomyces fradiae.
Research
2,504 papers- The tylosin-biosynthetic genes of Streptomyces fradiae.Antonie van Leeuwenhoek · 2001
- The effect of tylosin on antimicrobial resistance in beef cattle enteric bacteria: A systematic review and meta-analysis.Preventive veterinary medicine · 2020
- Efficient degradation of tylosin by Klebsiella oxytoca TYL-T1.The Science of the total environment · 2022
- Anti-Toxoplasma gondii effect of tylosin in vitro and in vivo.Parasites & vectors · 2024
- Tylosin exposure reduces the susceptibility of Salmonella Typhimurium to florfenicol and tetracycline.BMC veterinary research · 2020
via PubMed
Wikidata facts
- Mass
- 915.519
Show 5 more facts
- Commons category
- Tylosin
- chemical formula
- C₄₆H₇₇NO₁₇
- canonical SMILES
- CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
- isomeric SMILES
- CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
- World Health Organisation international non-proprietary name
- tylosin
via Wikidata · CC0
~6 min read
Article
9 sectionsContents
- Mode of action
- Spectrum of activity
- Clinical use
- Available forms
- Composition
- Precautions and contraindications
- Drug interactions
- See also
- References
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| tradename = Tylocine, Tylan | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =