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lymecycline
EntityQ897051· pop 17· linked from 167 articles

lymecycline

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Also known as N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)lysine, N-Lysinomethyltetracycline, Limeciclina, Tetracycline-L-methylene lysine, Tetracycline-L-methylenelysine, N(2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline, (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide, Lymecyclinum

Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed.

Research

201 papers

via PubMed

Wikidata facts

Subclass of
chemical compound
Mass
602.2588
Has use
medication
Show 7 more facts
significant drug interaction
isotretinoin
chemical formula
C₂₉H₃₈N₄O₁₀
World Health Organisation international non-proprietary name
lymecycline
canonical SMILES
CC1(C2=CC=CC(=C2C(=O)C3=C(C4(C(CC31)C(C(=C(C4=O)C(=O)NCNCCCCC(C(=O)O)N)O)N(C)C)O)O)O)O
subject has role
bactericide
isomeric SMILES
C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCNCCCC[C@@H](C(=O)O)N)N(C)C)O
Commons category
Lymecycline
Sources (1)

via Wikidata · CC0

~2 min read

Encyclopedic overview

6 sections
Contents
  • History
  • Indications
  • Acne
  • Side effects
  • See also
  • References

Lymecycline is a tetracycline broad-spectrum antibiotic. It is approximately 5,000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making use of the same fast and efficient mechanism by which carbohydrates are absorbed.

The greater absorption of lymecycline allows for lower dosages to be used; the standard dose of 408 mg is equivalent to 300 mg tetracycline base and, in its action, to 500 mg tetracycline hydrochloride. Lymecycline, unlike tetracycline hydrochloride, is soluble at all physiological pH values.

Excerpted from Wikipedia’s “lymecycline” article, available under the CC BY-SA 4.0 licence.

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