Structure via PubChem · Public domain (PubChem)
micronomicin
Sign in to saveAlso known as gentamicin C2b
Micronomicin (INN) is an aminoglycoside antibiotic for use on the eye.
Chemical data
- Formula
- C20H41N5O7
- Molecular weight
- 463.6 g/mol
- IUPAC name
- (2R,3R,4R,5R)-2-[(1S,2S,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
- SMILES
- C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H](C([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CNC)N)N)N)O
- InChIKey
- DNYGXMICFMACRA-KVJMWFOWSA-N
- XLogP
- -4.5
- Polar surface area
- 200 Ų
- H-bond donors
- 8
- H-bond acceptors
- 12
- Formal charge
- 0
via PubChem
Research
85 papers- [Micronomicin preparation].The Japanese journal of antibiotics · 1983
- [Review [new antibiotics series III]: micronomicin (author's transl)].The Japanese journal of antibiotics · 1982
- Metabolic reprogramming enhances the susceptibility of multidrug- and carbapenem-resistant bacteria to antibiotics.Nature microbiology · 2025
- Micronomicin/tobramycin binding with DNA: fluorescence studies using of ethidium bromide as a probe and molecular docking analysis.Journal of biomolecular structure & dynamics · 2019
- Antibiotic from Micromonospora.Annual review of microbiology · 1980
via PubMed
Wikidata facts
- Mass
- 463.3005986519999
Show 6 more facts
- chemical formula
- C₂₀H₄₁N₅O₇
- isomeric SMILES
- C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CNC)N)N)N)O
- NCI Thesaurus ID
- C90638
- subject has role
- antibiotic
- canonical SMILES
- OC1C(OCC(O)(C)C1NC)OC2C(O)C(OC3OC(CNC)CCC3N)C(N)CC2N
- Commons category
- Micronomicin
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | verifiedrevid = 437199317 | IUPAC_name = (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranoside | image = Micronomicin.svg | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration = Eye drops, IV
Excerpted from Wikipedia’s “micronomicin” article, available under the CC BY-SA 4.0 licence.