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GeneQ18046261· pop 6· linked from 16 articles

Also known as B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1

V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene.

Gene data

VTCN1
Name
V-set domain containing T cell activation inhibitor 1
Type
protein-coding
Aliases
B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

via MyGene.info

Gene · Ensembl

V-set domain containing T cell activation inhibitor 1

Symbol
VTCN1
Biotype
Protein coding
Organism
Homo sapiens
Location
1:117,142,381-117,210,960
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • See also
  • References
  • Further reading

V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene.

== Function ==

Excerpted from Wikipedia’s “VTCN1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

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