Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenskaالعربية
GeneQ18041514· pop 5· linked from 5 articles

WIPI1

Sign in to save

Also known as ATG18, ATG18A, WIPI49, WD repeat domain, phosphoinositide interacting 1

WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa), is a protein that in humans is encoded by the WIPI1 gene.

Gene data

WIPI1
Name
WD repeat domain, phosphoinositide interacting 1
Type
protein-coding
Position
68,420,948–68,457,563 (−)
Aliases
ATG18, ATG18A, WIPI49
Ensembl
ENSG00000070540
RefSeq RNA
NM_001320772.2, NM_017983.7, NR_135470.2, NR_135471.2, XM_017024808.2
RefSeq protein
NP_001307701.1, NP_060453.3, XP_016880297.1, XP_054172569.1

This gene encodes a WD40 repeat protein. Members of the WD40 repeat family are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].

Gene Ontology

Pathways

Autophagy - other - Homo sapiens (human)Autophagy - animal - Homo sapiens (human)Alzheimer disease - Homo sapiens (human)Amyotrophic lateral sclerosis - Homo sapiens (human)Huntington disease - Homo sapiens (human)Spinocerebellar ataxia - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)Shigellosis - Homo sapiens (human)MacroautophagyCellular responses to stress

via MyGene.info

Gene · Ensembl

WD repeat domain, phosphoinositide interacting 1

Symbol
WIPI1
Biotype
Protein coding
Organism
Homo sapiens
Location
17:68,420,948-68,457,563
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
117983
genomic end
66453654
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/55062
genomic start
66417089
chromosome
human chromosome 17
cytogenetic location
17q24.2
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Structure and function
  • See also
  • References
  • Further reading

WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1), also known as Atg18 protein homolog (ATG18) and WD40 repeat protein interacting with phosphoinositides of 49 kDa (WIPI 49 kDa), is a protein that in humans is encoded by the WIPI1 gene.

== Structure and function ==

Excerpted from Wikipedia’s “WIPI1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0