melanoma
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Key facts
- Medical condition.name
- Melanoma
- Medical condition.synonyms
- Malignant melanoma
- Medical condition.image
- Melanoma.jpg
- Medical condition.alt
- A back irregular Tumor by
- Medical condition.field
- Oncology and dermatology
- Medical condition.symptoms
- Mole that is increasing in size, has irregular edges, change in color, itchiness, or skin breakdown.
- Medical condition.causes
- Ultraviolet light (Sun, tanning devices)
- Medical condition.risks
- Family history, many moles, poor immune function
- Medical condition.diagnosis
- Tissue biopsy
- Medical condition.differential
- Seborrheic keratosis, lentigo, blue nevus, dermatofibroma
- Medical condition.prevention
- Sunscreen, avoiding UV light
- Medical condition.treatment
Research
182,643 papers- Histopathologic classification and prognostic factors of melanoma: a 2021 update.Italian journal of dermatology and venereology · 2021
- The 2018 World Health Organization Classification of Cutaneous, Mucosal, and Uveal Melanoma: Detailed Analysis of 9 Distinct Subtypes Defined by Their Evolutionary Pathway.Archives of pathology & laboratory medicine · 2020
- Immunotherapy in Acral and Mucosal Melanoma: Current Status and Future Directions.Frontiers in immunology · 2021
- Global trends in melanoma burden: A comprehensive analysis from the Global Burden of Disease Study, 1990-2021.Journal of the American Academy of Dermatology · 2025
- Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.Nature genetics · 2009
via PubMed
Article
43 sectionsContents
- Signs and symptoms
- Cause
- UV radiation
- Genetics
- Pathophysiology
- Gene mutations
- Metastasis
- Diagnosis
- Ugly duckling
- Biopsy
- Histopathologic types
- In situ or invasive
- Staging
- Laboratory
- Prevention
- Ultraviolet radiation
- Sunscreen
- Medications
- Treatment
- Surgery
- Add on treatment
- Chemotherapy
- Targeted therapy
- Immunotherapy
- Lentigo maligna
- Radiation
- Prognosis
- Epidemiology
- Australia
- United States
- History
- Terminology
- Research
- Targeted therapies
- BRAF inhibitors
- Ipilimumab
- Surveillance methods
- Oncolytic virotherapy
- Antivirals
- MicroRNAs
- Notes
- References
- External links
Melanoma is a type of cancer, typically skin cancer; it develops from the melanin-producing cells known as melanocytes. It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). In very rare cases melanoma can also happen in the lung, which is known as primary pulmonary melanoma and only happens in 0.01% of primary lung tumors.
In females, melanomas most commonly occur on the legs; while in men, on the back. Melanoma is frequently referred to as malignant melanoma. However, the medical community stresses that there is no such thing as a 'benign melanoma' and recommends that the term 'malignant melanoma' should be avoided as it is redundant.