YES1
Sign in to saveAlso known as HsT441, P61-YES, Yes, c-yes, YES proto-oncogene 1, Src family tyrosine kinase
protein-coding gene in the species Homo sapiens
Gene data
YES1- Name
- YES proto-oncogene 1, Src family tyrosine kinase
- Type
- protein-coding
- Position
- 721,587–813,276 (−)
- Aliases
- HsT441, P61-YES, Yes, c-yes
- Ensembl
- ENSG00000176105
- RefSeq RNA
- NM_005433.4, XM_005258139.5, XM_017025960.3, XM_024451243.2, XM_024451244.2
- RefSeq protein
- NP_005424.1, XP_005258196.1, XP_016881449.1, XP_024307011.1, XP_024307012.1
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
negative regulation of inflammatory response to antigenic stimulusnegative regulation of inflammatory response to antigenic stimuluscell surface receptor protein tyrosine kinase signaling pathwaycell differentiationT cell costimulationT cell costimulationprotein modification processFc-gamma receptor signaling pathway involved in phagocytosis
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
YES proto-oncogene 1, Src family tyrosine kinase
- Symbol
- YES1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:721,587-813,276
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein YES1 PDB 2hda.png
Show 8 more facts
- exact match
- identifiers.org/ncbigene/7525
- HomoloGene ID
- 55900
- found in taxon
- Homo sapiens
- genomic end
- 812547
- genomic start
- 721588
- chromosome
- human chromosome 18
- cytogenetic location
- 18p11.32
- expressed in
- lactiferous duct
Sources (4)
via Wikidata · CC0