AATK
Sign in to saveAlso known as AATYK, AATYK1, LMR1, LMTK1, PPP1R77, p35BP, apoptosis-associated tyrosine kinase, aatyk1
Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.
Gene data
LMTK1- Name
- lemur tail kinase 1
- Type
- protein-coding
- Position
- 81,110,487–81,166,228 (−)
- Aliases
- AATK, AATYK, AATYK1, LMR1, PPP1R77, p35BP
- Ensembl
- ENSG00000181409
- RefSeq RNA
- NM_001080395.3, NM_004920.3
- RefSeq protein
- NP_001073864.2, NP_004911.2
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
apoptosis associated tyrosine kinase
- Symbol
- AATK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,110,487-81,166,228
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Structure and expression
- Function
- References
- Further reading
- External links
Serine/threonine-protein kinase LMTK1 (also known as Apoptosis-associated tyrosine kinase) is an enzyme that in humans is encoded by the (AATK) gene.
==Structure and expression==
Excerpted from Wikipedia’s “AATK” article, available under the CC BY-SA 4.0 licence.