ZC3H12A
Sign in to saveAlso known as MCPIP, MCPIP1, dJ423B22.1, zinc finger CCCH-type containing 12A, Reg1, MCPIP-1
Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.
Gene data
ZC3H12A- Name
- zinc finger CCCH-type containing 12A
- Type
- protein-coding
- Aliases
- MCPIP, MCPIP-1, MCPIP1, Reg1, dJ423B22.1
ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.[supplied by OMIM, Mar 2008].
via MyGene.info
Gene · Ensembl
zinc finger CCCH-type containing 12A
- Symbol
- ZC3H12A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:37,474,496-37,484,379
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 11824
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/80149
- genomic end
- 37484377
- genomic start
- 37474580
- chromosome
- human chromosome 1
- cytogenetic location
- 1p34.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.
ZC3H12A (also known as MCPIP-1 and Regnase-1) is an MCP1 (CCL2; MIM 158105)-induced protein that plays an important role in cell differentiation, apoptosis and the regulation of inflammation.
Excerpted from Wikipedia’s “ZC3H12A” article, available under the CC BY-SA 4.0 licence.