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Biotechnology

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pyrosequencing
Pyrosequencing is a non-electrophoretic DNA sequencing (determining the order of nucleotides in DNA) method based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyrosequencing relies on light detection based on a chain reaction when pyrophosphate is released, hence, the name given it.
biotransformation
Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. Increasingly, biotransformations are effected with purified enzymes. Major industries and life-saving technologies depend on biotransformations.
polyclonal antibodies
type of immunoglobulin
bioleaching
REDIRECT Biohydrometallurgy
fixation
preservation of biological tissue
long non-coding RNA
non-protein coding transcripts longer than 200 nucleotides
DNA polymerase processivity factor complex
protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication
hyperaccumulator
thumb|Viola lutea subsp. calaminaria, also known as the zinc violet, grows in soils high in zinc.
xenobiology
Xenobiology (XB) is a subfield of synthetic biology, the study of synthesizing and manipulating biological devices and systems. The name "xenobiology" derives from the Greek word xenos, which means "stranger, alien". Xenobiology is a form of biology that is not (yet) familiar to science and is not found in nature. In practice, it describes novel biological systems and biochemistries that differ from the canonical DNA–RNA-20 amino acid system (see central dogma of molecular biology). For example, instead of DNA or RNA, the field of xenobiology explores nucleic acid analogues, termed xeno nuclei
protein engineering
biochemical and genetic engineering processes involved in the synthesis, modification, and production of protein products for various applications
bioelectronics
thumb|300px| A ribosome is a [[biological machine that utilizes protein domain dynamics, which can only be seen by neutron spin echo spectroscopy]]
organ-on-a-chip
An organ-on-a-chip (OOC) is a multi-channel 3D microfluidic cell culture, integrated circuit (chip) that simulates the activities, mechanics and physiological response of an entire organ or an organ system. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context. By acting as a more sophisticated in vitro approximation of complex tissues than standard cell culture, they provide the potential as an alternative to
necrophage
thumb|250x250px|Carcass of a shrew surrounded by multiple necrophages, including a blow fly and [[burying beetle.]] Necrophages (also known as carrion feeders) are animals that feed on decomposing dead animal biomass, such as the muscle and soft tissue of carcasses or corpses. The term derives from Greek , meaning 'dead', and , meaning 'to eat'. Many hundreds of necrophagous species have been identified including invertebrates in the insect, malacostracan and gastropod classes and vertebrates such as vultures, hyenas, quolls and wolves.
biomarker
Measurable indicator
palivizumab
Palivizumab, sold under the brand name Synagis, is a monoclonal antibody produced by recombinant DNA technology used to prevent severe disease caused by respiratory syncytial virus (RSV) infections. It is recommended for infants at high-risk for RSV due to conditions such as prematurity or other medical problems including heart or lung diseases.
inclusion body
cell component formed of aggregated molecules such as proteins or other biopolymers
Morpholino
chemical compound
biorobotics
Biorobotics is an interdisciplinary science that combines the fields of biomedical engineering, cybernetics, and robotics to develop new technologies that integrate biology with mechanical systems to develop more efficient communication, alter genetic information, and create machines that imitate biological systems.
antibody-drug conjugate
class of biopharmaceutical drug
virotherapy
Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These branches use three different types of treatment methods: gene overexpression, gene knockout, and suicide gene delivery. Gene overexpression adds genetic sequences that compensate for low to zero levels of needed gene expression. Gene knockout uses RNA methods to silence or reduce expression of disease-causing genes. Suicide g
Transfer DNA
type of DNA in bacterial genomes
Flavr Savr
vegetable
ChIP-sequencing
method used to analyze protein interactions with DNA
biocomputers
systems of biologically derived molecules that perform computational processes
Purpureocillium lilacinum
species of fungus
single-cell protein
edible unicellular microorganisms, specifically those high in protein
nucleic acid thermodynamics
The study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA)
PEGylation
thumb|Polyethylene glycol PEGylation (or pegylation) is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called macrogol) polymer chains to molecules and macrostructures, such as a drug, therapeutic protein or vesicle, which is then described as PEGylated. PEGylation affects the resulting derivatives or aggregates interactions, which typically slows down their coalescence and degradation as well as elimination in vivo.
Broad Institute
biomedical and genomic research center
Biohydrogen reactor
technics
DIY biology
biotechnological social movement
TNF inhibitor
pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF)
contract research organization
type of healthcare company
mutation breeding
process of exposing seeds to chemicals or radiation to generate mutants with desirable traits
DNA condensation
process of compacting DNA molecules
molecular diagnostics
subfield of biotechnology
micro-injection
thumb|Microinjection of a fluorescent dye into [[Ciona intestinalis eggs positioned in a microwell array.]]
somatic stem cell
multipotent stem cell in the adult body
axenic culture
In biology, axenic (, ) describes the state of a culture in which only a single species, variety, or strain of organism is present and entirely free of all other contaminating organisms. The earliest axenic cultures were of bacteria or unicellular eukaryotes, but axenic cultures of many multicellular organisms are also possible. Axenic culture is an important tool for the study of symbiotic and parasitic organisms in a controlled environment.
proteolysis targeting chimera
small molecule
amplicon
thumb|An amplicon sequence template that has been prepared for amplification. The target sequence to be amplified is colored green. In molecular biology, an amplicon is a piece of DNA that is the source and/or product of amplification or replication events. It can be formed artificially, using various methods including polymerase chain reactions (PCR) or ligase chain reactions (LCR), or naturally through gene duplication. In this context, amplification refers to the production of one or more copies of a genetic fragment or target sequence, specifically the amplicon. As it refers to the product
BamHI
BamHI (pronounced "Bam H one") (from Bacillus amyloliquefaciens) is a type II restriction endonuclease, having the capacity for recognizing short sequences (6 bp) of DNA and specifically cleaving them at a target site. This exhibit focuses on the structure-function relations of BamHI as described by Newman, et al. (1995). BamHI binds at the recognition sequence 5'-GGATCC-3', and cleaves these sequences just after the 5'-guanine on each strand. This cleavage results in sticky ends which are 4 bp long. In its unbound form, BamHI displays a central b sheet, which resides in between α-helices.
gene delivery
introduction of foreign genetic material into host cells
mycoremediation
thumb|Pleurotus ostreatus (Oyster mushroom)|300x300px Mycoremediation (from ancient Greek (), meaning "fungus", and the suffix , in Latin meaning 'restoring balance') is a form of bioremediation in which fungi-based remediation methods are used to decontaminate the environment. Fungi have been proven to be a cheap, effective and environmentally sound way for removing a wide array of contaminants from damaged environments or wastewater. These contaminants include heavy metals, organic pollutants, textile dyes, leather tanning chemicals and wastewater, petroleum fuels, polycyclic aromatic hydroc
knock-in
genetic engineering method
single cell sequencing
examines the sequence information from individual cells with optimized next-generation sequencing technologies
expression vector
plasmid specifically used for protein expression in the target
industrial fermentation
intentional use of fermentation by microorganisms
fed-batch
operational technique in biotechnological
somatic fusion
biological process
environmental biotechnology
biotechnology that is applied to and used to study the natural environment
electromethanogenesis
Electromethanogenesis is a form of electrofuel production where methane is produced by direct biological conversion of electrical current and carbon dioxide.
lipidomics
thumb|400px|Examples of various lipid species.
oncogenomics
Oncogenomics is a sub-field of genomics that characterizes cancer-associated genes. It focuses on genomic, epigenomic and transcript alterations in cancer.
somatic embryogenesis
method to derive a plant or embryo from a single somatic cell
pharming
genetic engineering to produce pharmaceuticals
Ion semiconductor sequencing
DNA sequencing method
Eadie–Hofstee diagram
graph of enzyme kinetics
Subcloning
thumb|300px|right|This image diagrams the procedure of subcloning as outlined to the left. In molecular biology, subcloning is a technique used to move a particular DNA sequence from a parent vector to a destination vector.
Helicase-dependent amplification
isothermic nucleic acid amplification test technology